Omalizumab (Xolair): Basic Information
Omalizumab (Xolair) is a preparation that is a protein of artificial origin, similar to proteins that are formed in our body. They belong to the class of monoclonal antibodies. Getting into our body, they block the substance of immunoglobulin E (IgE), which plays a key role in the formation of atopic bronchial asthma.
When is Xolair used?
This drug is prescribed as a basic therapy for severe atopic asthma in adults and children from 6 years of age. Indication for use is the lack of asthma control against the use of high doses of steroids and bronchodilator drugs.
A contraindication is an allergic reaction to the previous introduction.
The possibility of treatment with this drug is determined by the doctor.
Relative contraindications for use:
- chronic kidney or liver disease;
- autoimmune diseases in the stage of decompensation;
- living in a region where parasitic infections often occur, or a trip to such a region (this drug may weaken antiparasitic protection).
Xolair is not used to treat asthma exacerbation and does not relieve an asthma attack.
During pregnancy and breastfeeding, this medication should not be used unless the benefit is significantly greater than the risk.
The preparation is applied as an injection once every 2 or 4 weeks for 6 months.
Common side effects:
- high temperature;
- soreness in the area of injection;
- soreness in the upper abdomen.
Rare side effects:
- flu-like symptoms;
- weight gain.
Why is Xolair rarely used?
The main reason is the high price of the drug. It is not included in the compulsory medical insurance, but it can be delivered in state institutions on a quota basis (for example, in some children’s allergic centers, it is possible to get this drug free of charge).